2012 Publications

Publications resulting from human brain tissue obtained from the ABBN.

Schofield EC, Hodges JR, Bak TH, Xuereb JH, and Halliday GM. (2012) The relationship between clinical and pathological variables in Richardson's syndrome. J Neurol. 259: 482-490.

Abbott, C. and Gorrell, M. (2012) Dipeptidyl peptidase 8. In Handbook of Proteolytic Enzymes 3rd Edition. Amsterdam: Elsevier, pp. 3381-3386.

Benes FM. (2013) A New Paradigm for Understanding Gamma-Aminobutyric Acid Cell Pathology in Schizophrenia? BPS; 72: (9) 712-713.

Bromberg A, Lerer E, Udawela M, Scarr E, Dean B, Belmaker RH, Ebstein R, Agam G. (2012) Nicotinamide-N-methyltransferase (NNMT) in schizophrenia: genetic association and decreased frontal cortex mRNA levels. Int J Neuropsychopharmacol 15(6):727-737.

Brown RM. (2012) mGlu5 Receptor Functional Interaction and Addiction. Frontiers in Pharmacology. 3:84

Bull ND, Chidlow G, Wood JP, Martin KR, Casson RJ. (2012) The mechanism of axonal degeneration after perikaryal excitotoxic injury to the retina. Exp Neurol.; 236(1):34-45.

Casson RJ, Chidlow G, Ebneter A, Wood JP, Crowston J, Goldberg I. (2012) Translational neuroprotection research in glaucoma: a review of definitions and principles. Clin Experiment Ophthalmol.; 40(4):350-7.

Casson RJ. (2012) Pathogenesis of primary open-angle glaucoma. Clin Experiment Ophthalmol; 40(9):838-9.

Catts V S, Shannon Weickert C. (2012) Gene Expression Analysis Implicates a Death Receptor Pathway in Schizophrenia Pathology PLoS ONE; 7: (4) e35511.

Czech DP, Lee J, Sim H, Parish CL, Vilain E, Harley VR. (2012) The human testis-determining factor SRY localizes in midbrain dopamine neurons and regulates multiple components of catecholamine synthesis and metabolism. J Neurochem 122(2):260-271.

Dean B, Gibbons AS, Tawadros N, Brooks L, Everall IP, Scarr E. (2012) Different changes in cortical tumor necrosis factor- α -related pathways in schizophrenia and mood disorders. Mol Psychiatry 10.1038/mp.2012.95.

Farg MA, Soo KY, Walker AK, Pham H, Orian J, Horne MK, Warraich ST, Williams KL, Blair IP, Atkin JD. (2012) Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase. Neurobiol Aging 33(12):2855-2868.

Fodero-Tavoletti MT, Brockschnieder D, Villemagne VL, Martin L, Connor AR, Thiele A, Berndt M, McLean CA, Krause S, Rowe CC, Masters CL, Dinkelborg L, Dyrks T, Cappai R. (2012) In vitro characterization of [18F]-florbetaben, an A imaging radiotracer. Nucl Med Biol 39(7):1042-1048.

Frugier T, Conquest A, McLean C, Currie P, Moses D, Goldshmit Y. (2012) Expression and Activation of EphA4 in the Human Brain After Traumatic Injury. J Neuropathol Exp Neurol 71(3):242-250.

Gibbons AS, Brooks L, Scarr E, Dean B. (2012) AMPA receptor expression is increased post-mortem samples of the anterior cingulate from subjects with major depressive disorder. J Affect Disord 136(3):1232-1237.

Gibbons AS, Scarr E, Boer S, Money T, Jeon WJ, Felder C, Dean B. (2012) Widespread decreases in cortical muscarinic receptors in a subset of people with schizophrenia. Int J Neuropsychopharmacol. 17:1-10

Guerreiro PS, Huang Y, Gysbers A, Cheng D, Gai WP, Outeiro TF, Halliday GM. (2012) LRRK2 interactions with ?-synuclein in Parkinson's disease brains and in cell models. J Mol Med (Berl).

Huang Y, Chegini F, Chua G, Murphy K, Gai W, Halliday GM.(2012) Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T ?-synuclein mutation. Transl Neurodegener.; 1(1):2.

James SA, Volitakis I, Adlard PA, Duce JA, Masters CL, Cherny RA, Bush AI (2012) Elevated labile Cu is associated with oxidative pathology in Alzheimer disease. Free Radic Biol Med 52(2):298-302.

Janeczek P, MacKay RK, Lea RA, Dodd PR, Lewohl JM. (2012) Reduced expression of α-synuclein in alcoholic brain: influence of SNCA-Rep1 genotype Addiction Biology: epub

Jin Z, Bazov I, Kononenko O, Korpi ER, Bakalkin G, Birnir B. (2012) Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics. Frontiers in cellular neuroscience; 5: (30) 1-12. PMC3249692

Kim W. (2012) Changes in Sphingomyelin Level Affect Alpha-Synuclein and ABCA5 Expression. J Parkinsons Dis. 2012;2(1):41-6

Kister I, et al. (2012) MSBase Investigators. Increasing age at disability milestones among MS patients in the MSBase Registry. J Neurol Sci. ; 318(1-2):94-9

Kryger R, Fan L, Wilce PA, Jaquet V. (2012) MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics. Alcohol (Fayetteville, N.Y.): 46 (7) 629-634.

Lei P, Ayton S, Finkelstein DI, Spoerri L, Ciccotosto GD, Wright DK, Wong BX, Adlard PA,Cherny RA, Lam LQ, Roberts BR, Volitakis I, Egan GF, McLean CA, Cappai R, Duce JA, Bush AI (2012) Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Nat Med 18(2):291-295.

Manzardo AM, Henkhaus RS, Butler MG. (2012) Global DNA promoter methylation in frontal cortex of alcoholics and controls. Gene; 498: (1) 5-12.

Nunez YO, Mayfield RD. (2012) Understanding alcoholism through microRNA signatures in brains of human alcoholics. Frontiers in Genetics; 3 (43) 1-13 PMC 3322338.

Pamphlett R, Morahan JM, Luquin N, Yu B (2012) An approach to finding brain-situated mutations in sporadic Parkinson's disease. Parkinsonism Relat Disord 18(1):82-85.

Ponomarev I, Wang S, Zhang L, Harris RA, ad Mayfield RD. (2012) Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence Journal of Neuroscience; 32: (5) 1884-1897.

Qin L, Crews FT. (2012) NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegenerationi Journal of Neuroinflammation; 9: (1) 5.

Ramanan VK, et al. (2012) Alzheimer’s Disease Neuroimaging Initiative (ADNI). Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks. Brain Imaging Behav. ; 6(4):634-48.

Samson AL, Knaupp AS, Sashindranath M, Borg RJ, Au AE, Cops EJ, Saunders HM, Cody SH, McLean CA, Nowell CJ, Hughes VA, Bottomley SP, Medcalf RL. (2012) Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin. Cell Rep 2(4):889-901.

Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL. (2012) The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain 135(Pt 11):3251-3264.

Scarr E, Money TT, Pavey G, Neo J, Dean B. (2012) Mu opioid receptor availability in people with psychiatric disorders who died by suicide: a case control study. BMC Psychiatry 12:126.

Scarr E, Sundram S, Deljo A, Cowie TF, Gibbons AS, Juzva S, Mackinnon A, Wood SJ, Testa R, Pantelis C, Dean B. (2012) Muscarinic M1 receptor sequence: preliminary studies on its effects on cognition and expression. Schizophr Res 138(1):94-98.

Sequeira PA, Martin MV, Vawter MP. (2012) The first decade and beyond of transcriptional profiling in schizophrenia. Neurobiol Dis 45(1):23-36.

Sheedy D, Say M, Stevens J, Harper CG, Kril JJ. (2012) Influence of liver pathology on markers of postmortem brain tissue quality. Alcoholism: Clinical and Experimental Research; 36: (1) 55-60.

Soo KY, Atkin JD, Farg M, Walker AK, Horne MK, Nagley P. (2012) Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PLoS ONE 7(4):e35413.

Sun Y, Lim Y, Li F, Liu S, Lu JJ, Haberberger R, Zhong JH, Zhou XF. (2012) ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA. PLoS ONE; 7(4):e35883. doi: 10.1371/journal.pone.0035883.

Sundqvist N, Garrick T, Harding A. (2012) Families' reflections on the process of brain donation following coronial autopsy. Cell and Tissue Banking; 13: (1) 89-101. PMC3154613

Swaminathan S, et al. (2012) Alzheimer’s Disease Neuroimaging Initiative and NIA-LOAD/NCRAD Family Study Group. Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. PLoS ONE; 7(12):e50640.

Tang B, Capitao C, Dean B, Thomas EA. (2012) Differential age- and disease-related effects on the expression of genes related to the arachidonic acid signaling pathway in schizophrenia. Psychiatry Res 196(2-3):201-206.

Trojano M, et al. (2012) MSBase Study Group and the New Zealand MS Prevalence Study Group. Geographical variations in sex ratio trends over time in multiple sclerosis. PLoS One.; 7(10):e48078. doi: 10.1371/journal.pone.0048078.

Walker BM, Valdez GR, McLaughlin J P, Bakalkin G. (2012) Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence Alcohol (Fayetteville, N.Y.); 46: (4) 359-370.

Weickert CS, Tiwari Y, Schofield PR, Mowry BJ, Fullerton JM. (2012) Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity Translational Psychiatry; 2: (4) e104-8.

Wilson C, Abbott C. (2012). Dipeptidyl Peptidases: Substrates and Therapeutic Targeting in Human Health and Disease. In Proteinases as Drug Targets. London, UK: RSC Publishing, pp. 1-43.

Wong J, Higgins M, Halliday GM, Garner B. (2012) Amyloid beta selectively modulates neuronal TrkB alternative transcript expression with implications for Alzheimer's disease. Neuroscience; 210: 363-374.

Wu JQ, Wang X, Beveridge N J, Tooney PA, Scott RJ, Carr VJ, Cairns MJ.(2012) Transcriptome Sequencing Revealed Significant Alteration of Cortical Promoter Usage and Splicing in Schizophrenia PLoS ONE; 7: (4) e36351.

Yang GZ, Yang M, Lim Y, Lu JJ, Wang TH, Qi JG, Zhong JH, Zhou XF. (2012) Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons. J Neurochem; 122(5):1010-22.

2012 Book Chapters

Neo J, Udawela M, Dean B, Scarr E. (2012) Muscarinic receptors and nicotinic receptors as drug targets in disorders of the central nervous system. Book Chapter Advances in Medicine and Biology.